Why Fluffy French Bulldog Gene is so specific?

This Gene holds great specificity as the changes that this gene would result in, would lead to how and what kind of lifestyle the dog is going to have. This gene would affect the colour, sizes, length and thickness of the hair coat that is present over the body of the dog. This would ultimately influence the the economical margin and price of the dog and also quantify to the health scale.

What is the Fluffy gene and how is it formed?

Fluffy french bulldog results from a very rare gene mutation. The gene is called LH gene . This gene is formed in the osteoclasts of this dog. Formation of this gene is described in very complex medical terms that will be a little difficult to understand. So, the only thing we need to know is that the gene mutation is by this gene giving rise to 5FGF leading the fluffy dog.

How does Fluffy gene makes these dogs Fluffy?

The Fluffy gene forms a specific protein in the cells. It is called 5 Fibroblast Growth Factor . It is found in osteoclasts of fluffy french bulldogs. This growth factor genetically promotes the hair growth on the skin and results in Fluffy hairs short or long.

What characters does this LH gene have?

This gene promotes a few characters. Few of them are mentioned as follows: 1: It promoted the Hair growth on body 2: It gives them different colors and divides them in different types 3: It can also give rise to different cancers involving Blood and skin.

Fluffy French Bulldog Gene:

Fluffy French Bulldog Gene is the main difference which sets it apart from other dogs and in this case the french bulldogs. This gene is very rare and is found in only fluffy french bulldog. Fluffy French Bulldog Gene gives the dog its FLUFFY COAT hence the name FLUFFY french bulldog.

To understand this gene alteration, we would have to seep deep down into sea of medical genetics. The gene which gives this breed its specific characteristics is called as LH gene.

This gene contains a specific growth factor which is termed as 5FGF. Abbreviation of this growth factor would be 5-fibroblast growth factor. According to the medical point of view Fibroblast are basically cells present in the body that take part in growth on an organism.

In the said scenario, this growth factor is responsible for the growth of hair on this dogs body which sets it apart from other breeds of bulldogs. Fluffy French Bulldog Gene variation in cases could be very strong and could result in a thick long furry coat of the dog. But in some cases it also results in shot haired fluffy french bulldog.

This gene variation at the level of DNA would result in a recessive type of gene alteration that would lead to such change. In some cases it would lead to different results in terms of hair growth. Some percentage of dogs will be long haired and some would have a different growth change. They would grow as a fluffy french but would have short hairs. All this is dependent on outcome of the offspring and how it would turn out biologically. The given diagram would best describe my point.

One might ask, what lead to this specific change in this specie causing hair growth?

Well, in simplest form of words, this dog first resulted and appeared with such change as a cross between an English bulldog and Local ratter dog in France. This is very much debatable as many of the other people who existed in the 1800 had argued with this outcome. So this remains fairly arguable in every era.

But in todays technology, thanks to the DNA testing which allows us to use a genetic tool to help identify the breed is often used by the breeders to investigate the original pedigree.

So far it has been confirmed in many papers and with various genetic testings that this change was purely formed due to a coincidental change during an evolving phase. This genetic testing helps us reach to the 100% original breed.

This picture describes the origin of the very breed we are debating about.

References: 1. Housley DJ, Venta PJ. (2006) The long and the short of it: evidence that FGF5 is a major determinant of canine ‘hair’-itability. Anim Genet. Aug;37(4):309-15.

[Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/16879338]

2. Orivet Genetic Pet Care Australia [https://www.orivet.com]

3.Orivet French Bulldog Full Breed Profile [https://www.orivet.com/store/canine-full-breed-profile/french-bulldog—full-breed-profile]

4. Orivet Long Hair Gene (Canine DUP GG) – SINGLE ASSAY TEST [https://www.orivet.com/store/canine-trait/long-hair-gene-canine-c95f-]

Read More: All about Fluffy French Bulldog

FAQS:

Why Fluffy French Bulldog Gene is so specific?

This Gene holds great specificity as the changes that this gene would result in, would lead to how and what kind of lifestyle the dog is going to have. This gene would affect the colour, sizes, length and thickness of the hair coat that is present over the body of the dog. This would ultimately influence the the economical margin and price of the dog and also quantify to the health scale.
What is the Fluffy gene and how is it formed?

Fluffy french bulldog results from a very rare gene mutation. The gene is called LH gene. This gene is formed in the osteoclasts of this dog. Formation of this gene is described in very complex medical terms that will be a little difficult to understand. So, the only thing we need to know is that the gene mutation is by this gene giving rise to 5FGF leading the fluffy dog.
How does Fluffy gene makes these dogs Fluffy?

The Fluffy gene forms a specific protein in the cells. It is called 5 Fibroblast Growth Factor. It is found in osteoclasts of fluffy french bulldogs. This growth factor genetically promotes the hair growth on the skin and results in Fluffy hairs short or long.
What characters does this LH gene have?

This gene promotes a few characters. Few of them are mentioned as follows:
1: It promoted the Hair growth on body
2: It gives them different colors and divides them in different types
3: It can also give rise to different cancers involving Blood and skin.